Every now and then, science produces breakthroughs that change our understanding of what is possible.
- Most of us alive now don't remember what it was like before antibiotics.
- Many of us might not remember what it was like before laparoscopic surgeries. (I can still remember when all gallbladder surgeries required large incisions!)
In addition to innovations that help us treat disease, science has been exploring how to extend the quality and quantity of life. Since 2004, the National Institute on Aging (NIA) has been running a series of studies known as the Interventions Testing Program.
Over the years, the NIA has tested over 50 compounds that have "the potential to extend lifespan and delay disease and dysfunction". The studies are done with mice (because of course, you can't put humans in cages and control their diets!) Three different institutions conduct the tests on 3-5 compounds each year - ranging from pharmaceuticals to foods to nutritional supplements.
So far, the NIA has reported on 39 compounds from the first eight cohorts. Among those, six compounds extended life to a significant extent. Of those, only one was a dietary supplement - and it was Protandim Nrf2 Synergizer.
I've been sharing about my own experience with Protandim over the last nine months, so this was extremely interesting to me. Not everyone likes to read research like I do, though, so I'd like to highlight a few points that may be interesting to you too:
Protandim Nrf2 is the only life-extending compound that is not associated with side effects. The other five compounds reported to extend life are pharmaceuticals or compounds that have some associated risk.
Protandim Nrf2 stands out from other supplements. The study has looked at a number of well-known supplements including curcumin, green tea extract, fish oil, and resveratrol. None of these were shown to have an effect on life extension. That doesn't mean those things aren't good for us — they just don't have the same impact as Protandim.
Reported life extension was an average of 7%. That might not seem like a big deal, but in a typical human lifespan, that is roughly equal to five years.
Life-extendsion was reported for males, but not females. This has been true for several of the compounds. A likely explanation is because males of a species have a higher degree of oxidative stress and age more quickly. Female lifespan did improve with Protandim, but not enough to be statistically significant.
The amount of Protandim Nrf2 used was lower than recommended. It is interesting to note that for the first eight months of the intervention (from ages 9 to 17 months), the amount of Protandim that was fed to the mice was equivalent to only half of what is recommended for humans. So, we don't know what would have happened if they had been given the full dose.
So, what does this mean to us? If you are someone who is interested in supplements, the research now indicates that not only does Protandim Nrf2 Synergizer improve human functioning by lowering oxidative stress (an average of 40% in 30 days), it also has been shown to extend life.
I don't know anyone who wants to live forever, but most people would like to live a longer life, if it is a healthy one. The science of nutrigenomics is now placing that within reach!
What about you? What things are you doing to promote a longer healthier life? Please share your wisdom with us in the comments below.